|  | Dr.
                                      Eric Ravussin, Ph.D.
 Dr. Eric Ravussin is a Professor
                                  at the Pennington Biomedical Research Center
                                  in Baton Rouge and the Chief of the Division
                                  of "Health and Performance Enhancement".
                                  Dr. Ravussin is recognized internationally
                                  as a clinical investigator in the field of
                                  obesity and type 2 diabetes mellitus. He has
                                  made substantial contributions to the study
                                  of energy metabolism and its determinants.
                                  Dr. Ravussin was the first to identify four
                                  important metabolic predictors of weight gain
                                  in humans, i.e. a low metabolic rate, a low
                                  fat oxidation, a low spontaneous physical activity,
                                  and a lower activity of the sympathetic nervous
                                  activity. His former laboratory at the NIH
                                  was the first in the world in which all the
                                  components of energy expenditure could be measured
                                  using metabolic carts, respiratory chambers,
                                  and the doubly-labeled water technique. Dr.
                                  Ravussin was also the first investigator to
                                  combine the euglycemic hyperinsulinemic clamp
                                  with indirect calorimetry to separate glucose
                                  disposal into storage and oxidative metabolism.
                                  In the second part of the 1990s, Dr. Ravussin
                                  became involved in a genome-wide scan to identify
                                  obesity/diabetes susceptibility loci among
                                  Pima Indians. In his new role at the Pennington
                                  Biomedical Research Center, Dr. Ravussin will
                                  concentrate on the relationship between physiology
                                  and gene expression in response to diet and
                                  physical training. In
                                  1998, Dr Ravussin accepted the position of
                                  Director of Endocrine Research at the Lilly
                                  Research Laboratories in Indianapolis, Indiana. In
                                  2000, Dr Ravussin moved to the Pennington Biomedical
                                  Research Center to become the Chief of the
                                  Division of Health and Performance Enhancement.
                                  His research will focus on gene expression
                                  in human tissues in response to perturbation
                                  of energy balance in subjects prone or resistant
                                  to obesity. The effect of diet composition
                                  on performance and gene expression will also
                                  be studied. A new program focusing on prevention
                                  of childhood obesity has also been initiated.
                                  A functional genomics laboratory is now in
                                  place to examine the functional consequences
                                  of genetic polymorphisms on expression and
                                  function. 
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